Supplementary materials - analysis and correction of crosstalk effects in pathway analysis
نویسندگان
چکیده
Michele Donato, Zhonghui Xu, Alin Tomoiaga, James G. Granneman, Robert G. MacKenzie, Riyue Bao, Nandor Gabor Than, Peter H. Westfall, Roberto Romero, Sorin Draghici1,7∗ Computer Science Department, Wayne State University Perinatology Research Branch, NICHD/NIH Center for Advanced Analytics and Business Intelligence, Texas Tech University Center for Integrative Metabolic and Endocrine Research, Wayne State University Department of Biological Sciences, Wayne State University Department of Obstetrics and Gynecology, Wayne State University, School of Medicine Department of Clinical and Translational Science, Wayne State University
منابع مشابه
Analysis and correction of crosstalk effects in pathway analysis.
Identifying the pathways that are significantly impacted in a given condition is a crucial step in understanding the underlying biological phenomena. All approaches currently available for this purpose calculate a P-value that aims to quantify the significance of the involvement of each pathway in the given phenotype. These P-values were previously thought to be independent. Here we show that t...
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